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Библиография к Лекции №19.

Алефиров А.Н.

солодка рак предстательной железы, простата, фитотерапия, лечение, лекарственные растения, андрогены, эстрогены, побочные эффекты



Царь-зелье Аконит
© Алефиров, Санкт-Петербург,

©ИД "Весь", Санкт-Петербург, 2001

Полная энциклопедия гомеопатии
© Алефиров, Санкт-Петербург,
©ИД "Весь", Санкт-Петербург, 2001

Мастопатия. Лечение травами
© Алефиров, Санкт-Петербург,
©ИД "Весь", Санкт-Петербург, 2002

Рак. Я объявляю тебе войну!
© Алефиров, Санкт-Петербург,
©"Невский проспект", 2003

Фитотерапия заболеваний щитовидной железы,
© Алефиров, Санкт-Петербург, 2008,




1. Adams LS, Seeram NP, Hardy ML, Carpenter C, Heber D. Analysis of the interactions of botanical extract combinations against the viability of prostate cancer cell lines. Evid Based Complement Alternat Med. 2006 Mar;3(1):117-24.

2. Armanini D, Mattarello MJ, Fiore C, Bonanni G, Scaroni C, Sartorato P, Palermo M. Licorice reduces serum testosterone in healthy women. Steroids. 2004 Oct-Nov;69(11-12):763-6.

3. Armanini D, Bonanni G, Mattarello MJ, Fiore C, Sartorato P, Palermo M. Licorice consumption and serum testosterone in healthy man. Exp Clin Endocrinol Diabetes. 2003 Sep;111(6):341-3.

4. Armanini D, Bonanni G, Palermo M. Reduction of Serum Testosterone in Men by Licorice N Engl J Med 1999; 341:1158 October 7, 1999

5. Cheng CJ, Chen YH, Chau T, Lin SH. A hidden cause of hypokalemic paralysis in a patient with prostate cancer. Support Care Cancer. 2004 Nov;12(11):810-2.

6. Dong S, Inoue A, Zhu Y, Tanji M, Kiyama R. Activation of rapid signaling pathways and the subsequent transcriptional regulation for the proliferation of breast cancer MCF-7 cells by the treatment with an extract of Glycyrrhiza glabra root. Food Chem Toxicol. 2007 Dec;45(12):2470-8.




Солодка и эстрогены

Солодка и андрогены

Противоопухолевый эффект солодки

Побочные эффекты



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7. Fu Y, Hsieh TC, Guo J, Kunicki J, Lee MY, Darzynkiewicz Z, Wu JM. Licochalcone-A, a novel flavonoid isolated from licorice root (Glycyrrhiza glabra), causes G2 and late-G1 arrests in androgen-independent PC-3 prostate cancer cells. Biochem Biophys Res Commun. 2004 Sep 10;322(1):263-70.

8. Hawthorne S, Gallagher S. Effects of glycyrrhetinic acid and liquorice extract on cell proliferation and prostate-specific antigen secretion in LNCaP prostate cancer cells. J Pharm Pharmacol. 2008 May;60(5):661-6.

9. Hillerns PI, Zu Y, Fu YJ, Wink M. Binding of phytoestrogens to rat uterine estrogen receptors and human sex hormone-binding globulins. Z Naturforsch C. 2005 Jul-Aug;60(7-8):649-56.

10. Hsieh TC, Lu X, Chea J, Wu JM.Prevention and management of prostate cancer using PC-SPES: a scientific perspective. J Nutr. 2002 Nov;132(11 Suppl):3513S-3517S.

11. Hsieh TC, Wu JM. Mechanism of action of herbal supplement PC-SPES: elucidation of effects of individual herbs of PC-SPES on proliferation and prostate specific gene expression in androgen-dependent LNCaP cells. Int J Oncol. 2002 Mar;20(3):583-8.

12. Kanazawa M, Satomi Y, Mizutani Y, Ukimura O, Kawauchi A, Sakai T, Baba M, Okuyama T, Nishino H, Miki T. Isoliquiritigenin inhibits the growth of prostate cancer. Eur Urol. 2003 May;43(5):580-6.

13. Kang SC, Lee CM, Choi H, Lee JH, Oh JS, Kwak JH, Zee OP. Evaluation of oriental medicinal herbs for estrogenic and antiproliferative activities. Phytother Res. 2006 Nov;20(11):1017-9.

14. Lee YM, Lim do Y, Choi HJ, Jung JI, Chung WY, Park JH. Induction of cell cycle arrest in prostate cancer cells by the dietary compound isoliquiritigenin. J Med Food. 2009 Feb;12(1):8-14.

15. Leitolf H, Dixit KC, Higham CE, Brabant G. Licorice - or more? Exp Clin Endocrinol Diabetes. 2010 Apr;118(4):250-3.

16. Liu J, Burdette JE, Xu H, Gu C, van Breemen RB, Bhat KP, Booth N, Constantinou AI, Pezzuto JM, Fong HH, Farnsworth NR, Bolton JL. Evaluation of estrogenic activity of plant extracts for the potential treatment of menopausal symptoms. J Agric Food Chem. 2001 May;49(5):2472-9.

17. Mersereau JE, Levy N, Staub RE, Baggett S, Zogovic T, Chow S, Ricke WA, Tagliaferri M, Cohen I, Bjeldanes LF, Leitman DC. Liquiritigenin is a plant-derived highly selective estrogen receptor beta agonist. Mol Cell Endocrinol. 2008 Feb 13;283(1-2):49-57. Epub 2007 Nov 26.

18. Park SY, Lim SS, Kim JK, Kang IJ, Kim JS, Lee C, Kim J, Park JH. Hexane-ethanol extract of Glycyrrhiza uralensis containing licoricidin inhibits the metastatic capacity of DU145 human prostate cancer cells. Br J Nutr. 2010 Nov;104(9):1272-82.

19. Rafi MM, Vastano BC, Zhu N, Ho CT, Ghai G, Rosen RT, Gallo MA, DiPaola RS. Novel polyphenol molecule isolated from licorice root (Glycrrhiza glabra) induces apoptosis, G2/M cell cycle arrest, and Bcl-2 phosphorylation in tumor cell lines. J Agric Food Chem. 2002 Feb 13;50(4):677-84.

20. Seon MR, Lim SS, Choi HJ, Park SY, Cho HJ, Kim JK, Kim J, Kwon DY, Park JH. Isoangustone A present in hexane/ethanol extract of Glycyrrhiza uralensis induces apoptosis in DU145 human prostate cancer cells via the activation of DR4 and intrinsic apoptosis pathway. Mol Nutr Food Res. 2010 Sep;54(9):1329-39.

21. Shin S, Jang JY, Choi BI, Baek IJ, Yon JM, Hwang BY, Park D, Jeon JH, Nam SY, Yun YW, Kim YB. Licorice extract does not impair the male reproductive function of rats. Exp Anim. 2008 Jan;57(1):11-7.

22. Sigurjonsdottir HA, Axelson M, Johannsson G, Manhem K, Nystrom E, Wallerstedt S. Liquorice in moderate doses does not affect sex steroid hormones of biological importance although the effect differs between the genders. Horm Res. 2006;65(2):106-10.

23. Tamir S, Eizenberg M, Somjen D, Izrael S, Vaya J. Estrogen-like activity of glabrene and other constituents isolated from licorice root. J Steroid Biochem Mol Biol. 2001 Sep;78(3):291-8.

24. Yo YT, Shieh GS, Hsu KF, Wu CL, Shiau AL.Licorice and licochalcone-A induce autophagy in LNCaP prostate cancer cells by suppression of Bcl-2 expression and the mTOR pathway. J Agric Food Chem. 2009 Sep 23;57(18):8266-73.

25. Zamansoltani F, Nassiri-Asl M, Sarookhani MR, Jahani-Hashemi H, Zangivand AA. Antiandrogenic activities of Glycyrrhiza glabra in male rats. Int J Androl. 2009 Aug;32(4):417-22.


© Алефиров А.Н., 2001-2011